9 Ways to Increase Neuroplasticity: Your Brain’s Remarkable Ability to Change and Grow

By Dr. Nicole Cain ND, MA

Key Points:

Your brain is an extraordinary organ, capable of incredible feats of learning, adaptation, and growth. Imagine it as a vast network of intricate pathways, constantly adapting and evolving with each new experience, thought, or emotion. This remarkable ability of the brain to change and adapt is known as neuroplasticity, and it holds the key to unlocking our full potential for learning, development, and personal transformation.

What is Neuroplasticity?

For decades, scientists believed that the brain was largely hardwired, with its structure and function fixed from birth. However, groundbreaking research has revealed the brain’s remarkable plasticity, its ability to form new connections, strengthen existing ones, and even generate new neurons throughout life. This dynamic nature of the brain is fueled by neuroplasticity, the process by which our brains respond to stimuli and experiences, shaping our thoughts, behaviors, and even our very perception of the world.

Neuroplasticity, the brain’s remarkable ability to change and adapt, is the foundation for learning, memory, and overall cognitive function. It empowers us to overcome ingrained habits, develop new skills, and adapt to new experiences. This article delves into the fascinating world of neuroplasticity, exploring:

The Role of BDNF: Nurturing Brain Growth and Resilience

At the heart of neuroplasticity lies a protein called brain-derived neurotrophic factor (BDNF). BDNF acts as a fertilizer for the brain, promoting the growth and survival of neurons, enhancing the connections between them, and fostering the creation of new neural networks. This intricate dance of BDNF and neuroplasticity is essential for learning, memory formation, and overall cognitive function.

Harnessing the Power of Neuroplasticity: A Path to Personal Transformation

Neuroplasticity is not merely a scientific concept; it holds immense potential for personal transformation and growth. By understanding and harnessing the power of neuroplasticity, we can actively shape our brains and cultivate positive changes in our lives. Whether it’s overcoming ingrained habits, fostering new skills, or enhancing our overall cognitive function, neuroplasticity empowers us to take charge of our mental development and achieve our goals.

5 Lifestyle Strategies to Boost Neuroplasticity

While our brains may be naturally primed for plasticity, there are a number of lifestyle factors that can further enhance this remarkable ability and promote optimal brain health. By incorporating these strategies into your daily routine, you can actively nurture your brain’s capacity for change and growth:

  1. Embrace Physical Activity: Regular exercise has been shown to be a powerful stimulator of BDNF production, boosting neuroplasticity and enhancing cognitive function. Aim for at least 30 minutes of moderate-intensity exercise most days of the week.
  2. Nourish Your Brain with a Healthy Diet: A diet rich in fruits, vegetables, and whole grains provides essential nutrients that support brain health and promote BDNF production. Limit processed foods, sugary drinks, and unhealthy fats, which can hinder neuroplasticity.
  3. Prioritize Quality Sleep: Sleep plays a crucial role in brain consolidation and memory formation. Aim for 7-8 hours of uninterrupted sleep each night to allow your brain to rest, repair, and optimize neuroplasticity.
  4. Cultivate Mindfulness and Stress Management: Chronic stress can dampen BDNF production and impair neuroplasticity. Practices like mindfulness meditation, yoga, and spending time in nature can effectively reduce stress levels and promote brain health.
  5. Embrace Lifelong Learning: Keeping your mind engaged and actively learning new skills or knowledge is a potent stimulator of neuroplasticity. Take a class, learn a new language, or read a book to keep your brain challenged and growing.

4 Natural Remedies and Supplements to Increase Neuroplasticity (AKA increase BDNF)

In addition to lifestyle changes, there are several natural remedies and supplements that have been shown to increase brain-derived neurotrophic factor (BDNF), a protein that plays a crucial role in neuroplasticity. These natural allies can help you enhance your brain’s ability to learn, adapt, and grow.

  1. Lion’s Mane Mushroom (Hericium erinaceus): Lion’s mane mushroom, a popular adaptogen, has demonstrated neuroprotective and cognitive-enhancing effects. Studies suggest that it may promote BDNF production, potentially benefiting memory, learning, and overall brain health.
  2. Omega-3 Fatty Acids: Omega-3 fatty acids, particularly DHA (docosahexaenoic acid), are essential for brain function and development. Research indicates that omega-3 supplementation can increase BDNF levels, potentially improving cognitive function and reducing the risk of neurodegenerative diseases.
  3. Curcumin (Turmeric): Curcumin, the active compound in turmeric, has a wide range of health benefits, including neuroprotective effects. Studies show that curcumin can enhance BDNF production, potentially improving memory, learning, and mood.
  4. Lithium Orotate: Lithium orotate, a form of lithium, has gained attention for its potential to increase brain-derived neurotrophic factor (BDNF), a protein essential for brain health and cognitive function. Studies suggest that lithium orotate may improve mood and promote BDNF production, potentially offering benefits for memory, learning, and neuroprotection.

Psychedelic-Induced Neuroplasticity: Unlocking the Brain’s Remarkable Potential

For decades, psychedelics, such as psilocybin, MDMA, and LSD, have been shrouded in controversy and misconceptions. However, recent advancements in research have shed light on the remarkable potential of these substances to enhance neuroplasticity, the brain’s ability to change and adapt.

Certain psychedelics have been shown to promote neuroplasticity by increasing the production of brain-derived neurotrophic factor (BDNF), a protein that plays a key role in the growth and survival of neurons.

Studies have demonstrated that psychedelics can induce neuroplastic changes in regions of the brain associated with mood, emotion, and self-awareness. These changes have been linked to positive outcomes in the treatment of depression, anxiety, addiction, and post-traumatic stress disorder (PTSD).

Psilocybin, the active compound in psychedelic mushrooms, has been shown to increase BDNF production and promote the formation of new neural connections in the prefrontal cortex, a region of the brain associated with decision-making, problem-solving, and emotional regulation. This may explain psilocybin’s potential to alleviate symptoms of depression and anxiety.

MDMA, also known as ecstasy or molly, has been shown to increase BDNF production and enhance connectivity between brain regions involved in empathy and social bonding. This may explain MDMA’s potential to improve social functioning and reduce symptoms of PTSD.

LSD, a potent psychedelic, has been shown to increase BDNF production and promote the formation of new neural connections in multiple brain regions. This may explain LSD’s potential to induce mystical experiences and facilitate personal growth.

While research into psychedelics and neuroplasticity is still in its early stages, the findings suggest that these substances hold immense potential for treating a range of mental health conditions and promoting personal transformation. As research continues, we may uncover even more profound ways in which psychedelics can help us unlock the extraordinary potential of our brains.


The brain’s remarkable ability to change and adapt is a testament to its extraordinary potential. By embracing neuroplasticity and incorporating brain-boosting lifestyle practices, we can unlock the power of our minds to learn, grow, and transform. As we continue to explore the depths of neuroplasticity, we discover new possibilities for enhancing brain health, promoting mental well-being, and achieving our full potential.

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This article is for educational purposes only and is not intended as medical advice. Whenever considering changing your protocol whether it includes a change of medications, supplements, diet or lifestyle, always speak with your primary care physician first.

Dr. Nicole Cain is an advocate for empowering people around the world to help themselves via her educational free resources, online courses, and membership group. You can receive the tools you need to find the root cause of your symptoms and feel healthy again.